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Flu Shot Side Effects Explained: What Doctors and Medicare Want You to Know in 2026

cold flu shot
Photo by Subbotina Anna from Shutterstock

Possible Reactions and What to Expect

According to the CDC flu shot guidelines, common side effects include:

  • Soreness, redness, or swelling at the injection site
  • Headache or mild fever
  • Nausea
  • Muscle aches

These symptoms generally appear within a day or two and fade quickly. A dose of Tylenol or Ibuprofen, rest, and hydration can help you feel better.

In rare cases, fainting may occur shortly after vaccination, which is why it’s standard for healthcare providers to observe patients briefly after the shot.

If symptoms persist or worsen, reach out to your primary care physician or visit an urgent care center for a professional evaluation.

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