Vitamin C and vitamin B-12
Another unfortunate combination is vitamin C and vitamin B-12. Dobrynina recommends the doses of vitamin C and vitamin B12 to be taken at least two hours apart.
Also, Mayo Clinic explains that combining these two supplements can lower levels of vitamin B-12 in the body; and you don’t want a B-12 deficiency as it can lead to anemia, lower levels of healthy blood cells, causing a general state of fatigue, memory issues and even problems with mobility and balance.
See also:Vitamin B12 deficiency in Older Adults: 10 Signs and Symptoms You Should Know About
Vitamin E and vitamin K
Taking vitamin E and vitamin K together is also not the best idea due to their opposing effects on coagulation. According to various studies, vitamin E supplements can cause excessive bleeding in some individuals. To counteract such action, doctors recommend vitamin K. But taking them together annihilates the effect of vitamin K.
In a 2023 case study detailed in the Journal of Medical Case Reports, excessive supplementing of vitamin E can prevent vitamin K-derived coagulation factor synthesis. This can lead to serious bleeding incidents among which gastrointestinal bleeding and intracranial hemorrhage.
